Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.59 |
| ▸ | ACACA | Q13085 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178291 | 1.00 | ACACB (0.59) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL10264139 | 0.97 | ACACB (0.56) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL14293914 | 0.92 | ACACB (0.48) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL12092765 | 0.91 | ACACB (0.52) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL8897109 | 0.91 | FFAR1 (0.52) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL25479048 | 0.91 | ACACB (0.52) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL8895607 | 0.91 | FFAR1 (0.52) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL8897199 | 0.91 | ACACB (0.52) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL8897706 | 0.91 | ACACB (0.52) | ACACBACACAFFAR1FFAR4GPR84 | |
| SCHEMBL30483471 | 0.91 | ACACB (0.52) | ACACBACACAFFAR1FFAR4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257571-A1 | METHODS OF MAKING BEMPEDOIC ACID AND COMPOSITIONS OF THE SAME | ESPERION THERAPEUTICS, INC. (US) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020257573-A1 | SALT FORMS OF BEMPEDOIC ACID AND METHODS FOR USING THE SAME | ESPERION THERAPEUTICS, INC. (US) | 2020-12-24 | — | — | WO | disclosed |