Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22822107 | 0.94 | EGFR (0.83) | EGFR | |
| SCHEMBL22821709 | 0.92 | EGFR (0.71) | EGFR | |
| SCHEMBL22821782 | 0.92 | EGFR (0.80) | EGFR | |
| SCHEMBL30381642 | 0.91 | EGFR (1.00) | EGFR | |
| SCHEMBL22025688 | 0.91 | EGFR (1.00) | EGFR | |
| SCHEMBL22821808 | 0.91 | EGFR (0.70) | EGFR | |
| SCHEMBL22520134 | 0.90 | EGFR (0.86) | EGFR | |
| SCHEMBL22520127 | 0.90 | EGFR (0.86) | EGFR | |
| SCHEMBL22025654 | 0.90 | EGFR (0.86) | EGFR | |
| SCHEMBL22595133 | 0.90 | EGFR (0.85) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513029-B | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-112513029-A | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020253862-A1 | NITROGEN-CONTAINING ARYL PHOSPHORUS OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-24 | — | — | WO | disclosed |