SCHEMBL2282271

SCHEMBL2282271

CSC(c1nc(C)cc(C)n1)c1cccc(F)c1N

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
GRM5 P41594 2/20 0.32
SLC6A2 P23975 1/20 0.32
MAPT P10636 2/20 0.31
MITF O75030 1/20 0.31
MAPK1 P28482 1/20 0.31
MDM2 Q00987 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
GFER P55789 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2291751 0.89 KMT2A (0.34) MEN1KMT2AALDH1A1
SCHEMBL2286349 0.83 NR4A2 (0.40) MEN1KMT2ANOS3NOS2GRM5
SCHEMBL2287633 0.82 EDNRB (0.35) ALDH1A1
SCHEMBL2282195 0.81 KMT2A (0.35) MEN1KMT2ANOS3NOS2GRM5
SCHEMBL2289428 0.81 KMT2A (0.35) MEN1KMT2ANOS3NOS2GRM5
SCHEMBL5501978 0.81 KMT2A (0.36) MEN1KMT2ANOS3NOS2GRM5
SCHEMBL2287644 0.81 NPC1 (0.32)
SCHEMBL2291781 0.79 KMT2A (0.37) MEN1KMT2ANOS3NOS2GRM5
SCHEMBL2289583 0.79 KMT2A (0.34) MEN1KMT2AGRM5SLC6A2MAPT
SCHEMBL2285229 0.76 GAA (0.38) MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773124-B1 A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE BAYER CROPSCIENCE AG (DE) 2012-08-22 EP disclosed
US-8008484-B2 Use of sulfonanilides as agricultural and horticultural fungicide BAYER CROPSCIENCE AG (DE) 2011-08-30 US disclosed
US-20070219199-A1 Use of Sulfonanilides as Agricultural and Horticultural Fungicide BAYER CROPSCIENCE AG (DE) 2007-09-20 US disclosed
EP-1773124-A1 A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE Bayer CropScience Aktiengesellschaft (DE) 2007-04-18 EP disclosed
WO-2006008159-A1 A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE BAYER CROPSCIENCE AG (DE) 2006-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219199-A1 Use of Sulfonanilides as Agricultural and Horticultural Fungicide CBR3, CYP51A1, CBR1 MEN1 2408/4885KMT2A 1322/4885NOS3 454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.