SCHEMBL22823744

SCHEMBL22823744

CCC(=O)c1cc(Br)c(F)cc1O[C@@H](CF)COC(C)=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601805 1.00 HMGCR (0.30) HMGCR
SCHEMBL29602017 0.89 PTGDR2 (0.32)
SCHEMBL22823752 0.89 PTGDR2 (0.32)
SCHEMBL29369380 0.89 PTGDR2 (0.32)
SCHEMBL22823978 0.86 TSHR (0.33) HMGCR
SCHEMBL29368033 0.86 TSHR (0.33) HMGCR
SCHEMBL29602246 0.86 TSHR (0.33) HMGCR
SCHEMBL22823745 0.85 HMGCR (0.35) HMGCR
SCHEMBL29602355 0.85 HMGCR (0.35) HMGCR
SCHEMBL28676314 0.85 HMGCR (0.35) HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020254559-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2020-12-24 WO disclosed