Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697520 | 0.87 | KMT2A (0.37) | TSHRMAPTL3MBTL1TDP1AAK1 | |
| SCHEMBL28697521 | 0.87 | KMT2A (0.37) | TSHRMAPTL3MBTL1TDP1AAK1 | |
| SCHEMBL22805601 | 0.79 | SMN1; SMN2 (0.46) | GAATSHRMAPK1MAPTL3MBTL1 | |
| SCHEMBL22805604 | 0.79 | SMN1; SMN2 (0.46) | GAATSHRMAPK1MAPTL3MBTL1 | |
| SCHEMBL22823913 | 0.78 | AAK1 (0.37) | GAATSHRMAPK1MAPTL3MBTL1 | |
| SCHEMBL29602064 | 0.78 | AAK1 (0.37) | GAATSHRMAPK1MAPTL3MBTL1 | |
| SCHEMBL28676314 | 0.77 | HMGCR (0.35) | L3MBTL1AAK1HMGCRSMN1; SMN2ALDH1A1 | |
| SCHEMBL22823745 | 0.77 | HMGCR (0.35) | L3MBTL1AAK1HMGCRSMN1; SMN2ALDH1A1 | |
| SCHEMBL22823906 | 0.77 | MAPT (0.34) | GAATSHRMAPK1MAPTL3MBTL1 | |
| SCHEMBL29602355 | 0.77 | HMGCR (0.35) | L3MBTL1AAK1HMGCRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020254559-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2020-12-24 | — | — | WO | disclosed |