Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 1.00 |
| ▸ | TP53 | P04637 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | GMNN | O75496 | 2/20 | 1.00 |
| ▸ | KLF5 | Q13887 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | ATP1A1 | P05023 | 2/20 | 1.00 |
| ▸ | ATP1B1 | P05026 | 2/20 | 1.00 |
| ▸ | ATP1A3 | P13637 | 2/20 | 1.00 |
| ▸ | ATP1B2 | P14415 | 2/20 | 1.00 |
| ▸ | ATP1A2 | P50993 | 2/20 | 1.00 |
| ▸ | ATP1B3 | P54709 | 2/20 | 1.00 |
| ▸ | FXYD2 | P54710 | 2/20 | 1.00 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ouabain SCHEMBL14633742 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 | |
| Ouabain SCHEMBL17936503 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 | |
| Ouabain SCHEMBL2318232 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 | |
| Ouabain SCHEMBL10044992 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 | |
| Ouabain SCHEMBL24444049 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 | |
| Ouabain SCHEMBL18922524 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 | |
| Ouabain SCHEMBL24951415 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 | |
| Ouabain SCHEMBL21960066 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 | |
| Ouabain SCHEMBL21960068 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 | |
| Ouabain SCHEMBL14648716 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53LMNAHIF1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200400647-A1 | DEVICES AND SYSTEMS FOR MIMICKING HEART FUNCTION | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2020-12-24 | — | — | US | disclosed |