Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.85 |
| ▸ | HDAC1 | Q13547 | 19/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22827101 | 0.92 | BRD4 (1.00) | BRD4HDAC1 | |
| SCHEMBL22826873 | 0.91 | BRD4 (1.00) | BRD4HDAC1 | |
| SCHEMBL22827100 | 0.91 | BRD4 (1.00) | BRD4HDAC1 | |
| SCHEMBL22827096 | 0.89 | BRD4 (1.00) | BRD4HDAC1 | |
| SCHEMBL22827099 | 0.89 | BRD4 (1.00) | BRD4HDAC1 | |
| SCHEMBL22826834 | 0.89 | BRD4 (0.85) | BRD4HDAC1 | |
| SCHEMBL22826871 | 0.87 | BRD4 (1.00) | BRD4HDAC1 | |
| SCHEMBL22827041 | 0.87 | BRD4 (0.87) | BRD4HDAC1 | |
| SCHEMBL22826860 | 0.87 | BRD4 (1.00) | BRD4HDAC1 | |
| SCHEMBL22826833 | 0.86 | BRD4 (0.64) | BRD4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020253711-A1 | PYRROLOPYRIDONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2020-12-24 | — | — | WO | disclosed |