Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.68 |
| ▸ | SOS1 | Q07889 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25019491 | 0.82 | KRAS (0.69) | KRASSOS1 | |
| SCHEMBL21132935 | 0.81 | KRAS (1.00) | KRASSOS1 | |
| SCHEMBL22827502 | 0.81 | KRAS (1.00) | KRASSOS1 | |
| SCHEMBL22886898 | 0.81 | KRAS (1.00) | KRASSOS1 | |
| SCHEMBL25019960 | 0.71 | KRAS (0.83) | KRASSOS1 | |
| SCHEMBL25019962 | 0.71 | KRAS (0.70) | KRASSOS1 | |
| SCHEMBL26806875 | 0.71 | KRAS (1.00) | KRASSOS1 | |
| SCHEMBL22827568 | 0.71 | KRAS (0.82) | KRASSOS1 | |
| SCHEMBL22886913 | 0.71 | KRAS (1.00) | KRASSOS1 | |
| SCHEMBL21132674 | 0.70 | KRAS (1.00) | KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219493-A1 | BENZYLAMINO SUBSTITUTED PYRIDOPYRIMIDINONES AND DERIVATIVES AS SOS1 INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2023-08-02 | — | — | EP | disclosed |
| WO-2020254451-A1 | ANTICANCER COMBINATION THERAPY | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-12-24 | — | — | WO | disclosed |