SCHEMBL2282940

SCHEMBL2282940

N=S1(=O)CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1973309 0.96
SCHEMBL9820378 0.87
SCHEMBL3029034 0.67
SCHEMBL6652099 0.64
SCHEMBL22761495 0.63
SCHEMBL18552566 0.63
SCHEMBL23174551 0.61
SCHEMBL20549279 0.61
SCHEMBL9623859 0.61
SCHEMBL20526664 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 US disclosed
EP-4681774-A2 KHK INHIBITORS Gilead Sciences, Inc. (US) 2026-01-21 EP disclosed
EP-4313967-B1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2025-11-12 EP disclosed
US-12441707-B2 Indazole compounds TYRA BIOSCIENCES, INC. (US) 2025-10-14 US disclosed
EP-4619406-A1 TRICYCLIC COMPOUNDS Schrödinger, Inc. (US) 2025-09-24 EP disclosed
US-12410160-B2 KHK inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
CN-120192344-A Bicyclocompounds, preparation method and medical application thereof 上海济煜医药科技有限公司 2025-06-24 CN disclosed
WO-2025056068-A1 BICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 上海济煜医药科技有限公司 2025-03-20 WO disclosed
EP-4476204-A1 COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS Theras, Inc. (US) 2024-12-18 EP disclosed
CN-118619871-A Kv1.3 inhibitor and preparation method and application thereof 上海深势唯思科技有限责任公司 2024-09-10 CN disclosed
US-20090226377-A1 NOVEL SULPHOXIMINE-SUBSTITUTED QUINOLINE AND QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS BAYER HEALTHCARE LLC (DE) 2009-09-10 US disclosed
US-20090023782-A1 INCREASING PLANT VIGOR DOW AGROSCIENCES LLC (IN) 2009-01-22 US disclosed
WO-2008141843-A1 NOVEL SULPHOXIMINE-SUBSTITUTED QUINAZOLINE AND QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-11-27 WO disclosed
US-20080108667-A1 Multi-substituted pyridyl sulfoximines and their use as insecticides CORTEVA AGRISCIENCE LLC 2008-05-08 US disclosed
US-20080058394-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines DOW AGROSCIENCES LLC (US) 2008-03-06 US disclosed
US-20070203191-A1 Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines CORTEVA AGRISCIENCE LLC 2007-08-30 US disclosed
EP-0260042-B1 2-(1-OXO-1-IMINO-1-THIACYCLOALKYL)-THIOPENEM DERIVATIVES PFIZER INC. (US) 1991-12-27 EP disclosed
EP-0260042-A1 2-(1-Oxo-1-imino-1-thiacycloalkyl)-Thiopenem derivatives PFIZER INC. (US) 1988-03-16 EP disclosed
US-4556413-A POSTEMERGENCE AND PREEMERGENCE HERBICIDES HOFFMANN-LA ROCHE INC. (US) 1985-12-03 US disclosed
EP-0109575-A2 Benzoic-acid derivatives, process and means for its production F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-05-30 EP disclosed