SCHEMBL22829569

SCHEMBL22829569

CC(N)C(N)=O.CCCCCNC(C(=O)O)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.54
PLA2G2A P14555 1/20 0.45
PLA2G5 P39877 1/20 0.45
NOD1 Q9Y239 1/20 0.39
DPP7 Q9UHL4 2/20 0.39
TP53 P04637 2/20 0.39
PPARG P37231 2/20 0.37
PPARA Q07869 1/20 0.37
EPHX1 P07099 5/20 0.37
RRM1 P23921 1/20 0.36
GAA P10253 1/20 0.36
GRIK1 P39086 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
GRIK2 Q13002 1/20 0.36
SLC15A1 P46059 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1818420 0.90 SMN1; SMN2 (0.64) SMN1; SMN2PLA2G2APLA2G5TP53PPARG
SCHEMBL28083305 0.88 SMN1; SMN2 (0.62) SMN1; SMN2PLA2G2APLA2G5TP53PPARG
SCHEMBL28158383 0.88 SMN1; SMN2 (0.62) SMN1; SMN2PLA2G2APLA2G5TP53PPARG
SCHEMBL28439323 0.88 SMN1; SMN2 (0.62) SMN1; SMN2PLA2G2APLA2G5TP53PPARG
SCHEMBL11581195 0.88 SMN1; SMN2 (0.62) SMN1; SMN2PLA2G2APLA2G5TP53PPARG
SCHEMBL11581198 0.88 SMN1; SMN2 (0.62) SMN1; SMN2PLA2G2APLA2G5TP53PPARG
SCHEMBL31743456 0.88 SMN1; SMN2 (0.62) SMN1; SMN2PLA2G2APLA2G5TP53PPARG
SCHEMBL28014633 0.86 SMN1; SMN2 (0.60) SMN1; SMN2PLA2G2APLA2G5TP53PPARG
SCHEMBL27510235 0.86 SMN1; SMN2 (0.60) SMN1; SMN2PLA2G2APLA2G5TP53PPARG
SCHEMBL28013952 0.86 SMN1; SMN2 (0.60) SMN1; SMN2PLA2G2APLA2G5TP53PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118304212-A Topical compositions containing N-acyl dipeptide derivatives and glycolic acid 强生消费者公司 2024-07-09 CN disclosed
US-20240148632-A1 TOPICAL COMPOSITIONS CONTAINING N-ACYL DIPEPTIDE DERIVATIVES AND GLYCOLIC ACID KENVUE BRANDS LLC 2024-05-09 US disclosed
US-20200405609-A1 TOPICAL COMPOSITIONS CONTAINING N-ACYL DIPEPTIDE DERIVATIVES AND GLYCOLIC ACID JOHNSON & JOHNSON CONSUMER INC. 2020-12-31 US disclosed
EP-3756731-A1 TOPICAL COMPOSITIONS CONTAINING N-ACYL DIPEPTIDE DERIVATIVES AND GLYCOLIC ACID JOHNSON & JOHNSON CONSUMER INC. (US) 2020-12-30 EP disclosed
CN-112137911-A Topical composition containing N-acyl dipeptide derivative and glycolic acid 强生消费者公司 2020-12-29 CN disclosed