Oxedrine

Oxedrine

SCHEMBL2283013

CNC[C@H](O)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 1.00
HIF1A Q16665 6/20 1.00
TDP1 Q9NUW8 6/20 1.00
BLM P54132 4/20 1.00
TAAR1 Q96RJ0 3/20 1.00
ALDH1A1 P00352 2/20 1.00
HTR1A P08908 2/20 1.00
THPO P40225 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
NMUR2 Q9GZQ4 1/20 1.00
CYP2C9 P11712 1/20 1.00
ADRB2 P07550 5/20 0.63
ADRA2A P08913 4/20 0.63
ADRA2B P18089 4/20 0.63
ADRA2C P18825 4/20 0.63
TSHR P16473 4/20 0.63
ADRB1 P08588 3/20 0.63
ADRB3 P13945 3/20 0.63
MAPT P10636 3/20 0.63
HSD17B10 Q99714 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxedrine SCHEMBL146500 1.00 KDM4E (1.00) KDM4EHIF1ATDP1BLMTAAR1
Oxedrine SCHEMBL17726874 1.00 KDM4E (1.00) KDM4EHIF1ATDP1BLMTAAR1
Oxedrine SCHEMBL28287981 1.00 KDM4E (1.00) KDM4EHIF1ATDP1BLMTAAR1
Oxedrine SCHEMBL1487703 0.98 KDM4E (0.96) KDM4EHIF1ATDP1BLMTAAR1
SCHEMBL28858225 0.94 HIF1A (0.89) KDM4EHIF1ATDP1BLMTAAR1
SCHEMBL28193633 0.94 HIF1A (0.89) KDM4EHIF1ATDP1BLMTAAR1
Oxedrine SCHEMBL28002395 0.91 HIF1A (0.82) KDM4EHIF1ATDP1BLMTAAR1
Oxedrine SCHEMBL30559825 0.88 KDM4E (0.77) KDM4EHIF1ATDP1BLMTAAR1
Oxedrine SCHEMBL146499 0.88 KDM4E (0.77) KDM4EHIF1ATDP1BLMTAAR1
Halostachine SCHEMBL28853304 0.86 HIF1A (0.75) KDM4EHIF1ATDP1BLMTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041652-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INT (US) 2026-02-12 US claimed
WO-2024118094-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INTERNATIONAL (US) 2024-06-06 WO claimed
CN-107427479-B System and method for preventing hair loss 芙丽雅国际公司 2021-03-30 CN claimed
EP-3217967-B1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INT (US) 2019-09-18 EP claimed
US-10238593-B2 System and method for preventing alopecia FOLLEA INTERNATIONAL (US) 2019-03-26 US claimed
CN-107427479-A The system and method for anti-alopecia-stopping 芙丽雅国际公司 2017-12-01 CN claimed
US-20170333316-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INTERNATIONAL (US) 2017-11-23 US claimed
EP-3217967-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA Follea International (US) 2017-09-20 EP claimed
WO-2016077744-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA GOREN OFER A (US) 2016-05-19 WO claimed
WO-2026106796-A1 SYSTEM AND METHOD FOR THE TREATMENT OF TELOGEN EFFLUVIUM, ANDROGENETIC ALOPECIA, AND OTHER HAIR LOSS DISORDERS FOLLEA INTERNATIONAL (US) 2026-05-21 WO disclosed
US-20260041652-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INT (US) 2026-02-12 US disclosed
WO-2024118094-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INTERNATIONAL (US) 2024-06-06 WO disclosed
US-20230338309-A1 COMPOSITIONS AND METHODS FOR TOPICAL TREATMENT OF VASCULAR CONDITIONS JSS RESEARCH, LLC 2023-10-26 US disclosed
CN-116930388-A Method for screening brain tissue markers of Parkinson model mice based on metabonomics 苏州大学附属第二医院 2023-10-24 CN disclosed
WO-2011103130-A1 AMINOTHIAZOLONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-08-25 WO disclosed
US-20110200586-A1 AMINOTHIAZOLONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-08-18 US disclosed
CN-102040529-A Method for synthesizing synephrine hydrochloride HANGZHOU FST PHARMACEUTICAL CO LTD 2011-05-04 CN disclosed
CN-101792394-A Extraction separation method of L-synephrine UNIV CHONGQING 2010-08-04 CN disclosed
CN-1031643-C Novel glycoside compounds and production and use thereof HARRIER INC (US) 1996-04-24 CN disclosed
CN-1073179-A Novel glycoside compounds and preparation thereof and purposes HARRIER INC (US) 1993-06-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041652-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA DYRK4, DYRK2, STRA6 KDM4E 1963/4885HIF1A 3522/4885TDP1 906/4885
US-20110200586-A1 AMINOTHIAZOLONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS ESR2, ESRRA, ESRRG KDM4E 2936/4885HIF1A 186/4885TDP1 2709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.