Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12439631 | 1.00 | NR1I2 (0.56) | NR1I2CYP2E1 | |
| SCHEMBL2218884 | 1.00 | NR1I2 (0.56) | NR1I2CYP2E1 | |
| SCHEMBL2216739 | 0.96 | NR1I2 (0.57) | NR1I2CYP2E1 | |
| SCHEMBL12439473 | 0.93 | NR1I2 (0.60) | NR1I2CYP2E1 | |
| SCHEMBL2219255 | 0.92 | NR1I2 (0.56) | NR1I2CYP2E1 | |
| SCHEMBL12439447 | 0.92 | NR1I2 (0.60) | NR1I2CYP2E1 | |
| SCHEMBL12514090 | 0.90 | NR1I2 (0.42) | NR1I2CYP2E1 | |
| SCHEMBL12439472 | 0.88 | NR1I2 (0.62) | NR1I2CYP2E1 | |
| SCHEMBL12439627 | 0.88 | NR1I2 (0.55) | NR1I2CYP2E1 | |
| SCHEMBL12439624 | 0.88 | NR1I2 (0.55) | NR1I2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523951-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | Gilead Sciences, Inc. (US) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011088303-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES , INC. (US) | 2011-07-21 | — | — | WO | disclosed |