⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22835025 | 0.76 | — | — | |
| SCHEMBL19029766 | 0.76 | PIM1 (0.33) | — | |
| SCHEMBL22835139 | 0.72 | — | — | |
| SCHEMBL22834893 | 0.72 | — | — | |
| SCHEMBL8104798 | 0.63 | — | — | |
| SCHEMBL25157822 | 0.59 | PIK3CA (0.43) | — | |
| SCHEMBL19102376 | 0.59 | FLT3 (0.39) | — | |
| SCHEMBL3037759 | 0.59 | FLT3 (0.39) | — | |
| SCHEMBL17759350 | 0.56 | FLT3 (0.44) | — | |
| SCHEMBL15951841 | 0.56 | CDK2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979654-B | Heteroaryl fused ring compounds, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2024-03-19 | — | — | CN | disclosed |
| US-20230087118-A1 | IMIDAZO[1,2-a]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | BIOGEN MA INC. | 2023-03-23 | — | — | US | disclosed |
| EP-3990454-A1 | IMIDAZO[1,2-A]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | Biogen MA Inc. (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-112979654-A | Heteroaryl fused ring compound, preparation method and application thereof | 成都倍特药业有限公司 | 2021-06-18 | — | — | CN | disclosed |
| WO-2020263980-A1 | IMIDAZO[1,2-A]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | BIOGEN MA INC. (US) | 2020-12-30 | — | — | WO | disclosed |