⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176440 | 0.88 | — | — | |
| SCHEMBL20176555 | 0.87 | — | — | |
| SCHEMBL20176619 | 0.86 | — | — | |
| SCHEMBL20176377 | 0.80 | SLC6A4 (0.35) | — | |
| SCHEMBL20176664 | 0.74 | SLC6A4 (0.35) | — | |
| SCHEMBL20176885 | 0.74 | SLC6A2 (0.53) | — | |
| Hydrochloric Acid SCHEMBL20168801 | 0.73 | SLC6A4 (0.34) | — | |
| SCHEMBL20176912 | 0.72 | SLC6A2 (0.30) | — | |
| SCHEMBL30357902 | 0.70 | — | — | |
| SCHEMBL20165883 | 0.70 | SLC6A4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541784-B1 | NOVEL AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | INTEGRATIVE RES LABORATORIES SWEDEN AB (SE) | 2023-09-13 | — | — | EP | disclosed |
| US-10875829-B1 | Azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission | INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB (SE) | 2020-12-29 | — | — | US | disclosed |