Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SOD1 | P00441 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18629006 | 1.00 | NPSR1 (0.35) | NPSR1MAPTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL27196415 | 0.98 | NPSR1 (0.34) | NPSR1MAPTMEN1KMT2APOLB | |
| SCHEMBL2340414 | 0.89 | NPSR1 (0.33) | NPSR1MAPTMEN1KMT2APOLB | |
| SCHEMBL2340412 | 0.89 | NPSR1 (0.33) | NPSR1MAPTMEN1KMT2APOLB | |
| SCHEMBL17064244 | 0.89 | NPSR1 (0.33) | NPSR1MAPTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL17062254 | 0.87 | NPSR1 (0.32) | NPSR1MAPTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL17064251 | 0.87 | NPSR1 (0.32) | NPSR1MAPTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL17062207 | 0.87 | NPSR1 (0.32) | NPSR1MAPTMEN1KMT2APOLB | |
| SCHEMBL1543229 | 0.81 | F10 (0.36) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL21576490 | 0.81 | NPSR1 (0.33) | NPSR1MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10874673-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10874673-B2 | Inhibitors of influenza viruses replication | ACE, IRF3, ACE2 | NPSR1 2470/4885MAPT 3275/4885MEN1 3469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.