Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.61 |
| ▸ | EGLN2 | Q96KS0 | 17/20 | 0.61 |
| ▸ | EGLN3 | Q9H6Z9 | 17/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17629656 | 0.87 | EGLN1 (0.64) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL19251693 | 0.85 | EGLN1 (0.78) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL17629663 | 0.80 | EGLN1 (0.66) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL13017097 | 0.79 | EGLN1 (0.66) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL17629627 | 0.79 | EGLN1 (0.75) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL17629635 | 0.79 | EGLN1 (0.71) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL17629657 | 0.78 | EGLN1 (0.70) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL22838664 | 0.78 | EGLN1 (0.78) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL17629641 | 0.78 | EGLN1 (0.75) | EGLN1EGLN2EGLN3CYSLTR2 | |
| SCHEMBL17629654 | 0.78 | EGLN1 (0.80) | EGLN1EGLN2EGLN3CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197455-B1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME (US) | 2020-12-30 | — | — | EP | disclosed |