Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 18/20 | 0.83 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11977593 | 0.91 | FOLH1 (1.00) | FOLH1 | |
| SCHEMBL24336825 | 0.91 | FOLH1 (1.00) | FOLH1 | |
| SCHEMBL24585283 | 0.85 | FOLH1 (0.77) | FOLH1FPR2 | |
| SCHEMBL20312210 | 0.84 | FOLH1 (0.72) | FOLH1FPR2 | |
| SCHEMBL22466340 | 0.81 | FOLH1 (0.79) | FOLH1 | |
| SCHEMBL22466339 | 0.81 | FOLH1 (0.79) | FOLH1 | |
| SCHEMBL11977622 | 0.79 | FOLH1 (1.00) | FOLH1 | |
| SCHEMBL4673746 | 0.79 | FOLH1 (1.00) | FOLH1 | |
| SCHEMBL4336024 | 0.79 | FOLH1 (1.00) | FOLH1 | |
| SCHEMBL11977600 | 0.79 | FOLH1 (1.00) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3335736-B1 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARM INC (US) | 2020-12-30 | — | — | EP | disclosed |