Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 17/20 | 0.48 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22843527 | 1.00 | NT5E (0.48) | NT5EKCNN3PDE1CPDE9A | |
| SCHEMBL22843563 | 0.88 | NT5E (0.56) | NT5E | |
| SCHEMBL22843589 | 0.88 | NT5E (0.56) | NT5E | |
| SCHEMBL22843594 | 0.86 | NT5E (0.49) | NT5EKCNN3PDE1CPDE9A | |
| SCHEMBL22843558 | 0.86 | NT5E (0.49) | NT5EKCNN3PDE1CPDE9A | |
| SCHEMBL22843574 | 0.84 | NT5E (0.42) | NT5E | |
| SCHEMBL22843665 | 0.82 | NT5E (0.58) | NT5E | |
| SCHEMBL22843599 | 0.82 | NT5E (0.56) | NT5E | |
| SCHEMBL22843592 | 0.82 | NT5E (0.56) | NT5E | |
| SCHEMBL22843457 | 0.81 | NT5E (0.59) | NT5EPDE1CPDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200405629-A1 | PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS | ARCUS BIOSCIENCES, INC. | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405629-A1 | PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS | NT5C2, ADA, ENTPD1 | NT5E 10/4885KCNN3 2913/4885PDE1C 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.