Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188934 | 1.00 | TSHR (0.35) | TSHRCA1CA2CA4ALDH1A1 | |
| SCHEMBL24923170 | 0.85 | TDP1 (0.41) | TSHRCA1CA2CA4 | |
| SCHEMBL14465957 | 0.85 | CA1 (0.36) | CA1CA2CA4 | |
| SCHEMBL5436274 | 0.78 | — | — | |
| SCHEMBL23082583 | 0.78 | — | — | |
| SCHEMBL1192834 | 0.78 | — | — | |
| SCHEMBL23082584 | 0.78 | — | — | |
| SCHEMBL25133152 | 0.78 | — | — | |
| SCHEMBL4688269 | 0.78 | — | — | |
| SCHEMBL14574289 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200405874-A1 | METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES | IMMUNOGEN, INC. | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405874-A1 | METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES | EPCAM, CD2BP2, XPA | TSHR 2222/4885CA1 293/4885CA2 1600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.