Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22844929 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2CA2HDAC3HDAC1CA12 | |
| SCHEMBL22844962 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2CA2HDAC3HDAC1CA12 | |
| SCHEMBL29531140 | 0.83 | CRBN (0.41) | SMN1; SMN2CA2HDAC3HDAC1CA12 | |
| SCHEMBL22845092 | 0.81 | HDAC3 (0.46) | SMN1; SMN2CA2HDAC3HDAC1NPC1 | |
| SCHEMBL17039696 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2CA2HDAC3HDAC1NAMPT | |
| SCHEMBL24796096 | 0.75 | MEN1 (0.40) | SMN1; SMN2CA2HDAC3HDAC1CA12 | |
| SCHEMBL15757525 | 0.75 | MEN1 (0.40) | SMN1; SMN2CA2HDAC3HDAC1CA12 | |
| SCHEMBL17841946 | 0.74 | MEN1 (0.37) | SMN1; SMN2CA2HDAC3HDAC1CA12 | |
| SCHEMBL21142116 | 0.74 | SMN1; SMN2 (0.66) | SMN1; SMN2CA2HDAC3HDAC1NPC1 | |
| SCHEMBL16619189 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2HDAC3HDAC1ALBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020260514-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | THE UNIVERSITY OF BATH (GB) | 2020-12-30 | — | — | WO | disclosed |