Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24712763 | 0.81 | CRBN (0.47) | ALDH1A1 | |
| SCHEMBL22006041 | 0.80 | TSHR (0.41) | KDM4EALDH1A1POLBHTR2AHTR2C | |
| SCHEMBL19629754 | 0.76 | TSHR (0.43) | KDM4EALDH1A1POLBHTR2AHTR2C | |
| SCHEMBL22845277 | 0.73 | DDB1 (0.52) | ALDH1A1HTR2B | |
| SCHEMBL22939207 | 0.73 | DDB1 (0.39) | KDM4EALDH1A1HTR2CHTR2BPKM | |
| SCHEMBL19612069 | 0.70 | DDB1 (0.51) | ALDH1A1HTR2B | |
| SCHEMBL19612072 | 0.70 | DDB1 (0.51) | ALDH1A1HTR2B | |
| SCHEMBL19387907 | 0.69 | CRBN (0.59) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL21207999 | 0.68 | CRBN (0.58) | ALDH1A1 | |
| SCHEMBL21107417 | 0.68 | CRBN (0.58) | ALDH1A1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263935-A1 | HCK DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |