Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19477877 | 0.87 | MEN1 (0.46) | MEN1KMT2ACA2HPGDALDH1A1 | |
| SCHEMBL25866786 | 0.85 | KMT2A (0.50) | MEN1KMT2AHPGDANPEPDNPEP | |
| SCHEMBL11912094 | 0.84 | MEN1 (0.50) | MEN1KMT2ACA2HPGDALDH1A1 | |
| SCHEMBL23334288 | 0.84 | MEN1 (0.50) | MEN1KMT2ACA2HPGDALDH1A1 | |
| SCHEMBL21029891 | 0.84 | MEN1 (0.50) | MEN1KMT2ACA2HPGDALDH1A1 | |
| SCHEMBL25118082 | 0.84 | KMT2A (0.50) | MEN1KMT2ACA2HPGDALDH1A1 | |
| SCHEMBL25118084 | 0.84 | MEN1 (0.50) | MEN1KMT2AHPGDALDH1A1TDP1 | |
| SCHEMBL24982780 | 0.84 | MEN1 (0.50) | MEN1KMT2AHPGDALDH1A1TDP1 | |
| SCHEMBL11912095 | 0.84 | MEN1 (0.50) | MEN1KMT2ACA2HPGDALDH1A1 | |
| SCHEMBL26031870 | 0.84 | MEN1 (0.50) | MEN1KMT2ACA2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263935-A1 | HCK DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |