SCHEMBL22848255

SCHEMBL22848255

CC1(C)/C(=C\C=C2C(=O)c3cc4ccccc4cc3C2=O)N(c2c(F)cccc2F)c2ccc3ccccc3c21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 9/20 0.37
MAPT P10636 4/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
HTT P42858 2/20 0.34
NPC1 O15118 1/20 0.34
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PRMT5 O14744 1/20 0.33
PRMT8 Q9NR22 1/20 0.33
BLM P54132 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP1B1 Q16678 1/20 0.32
GAA P10253 2/20 0.31
KDM4E B2RXH2 2/20 0.31
LMNA P02545 2/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848164 0.88 PRMT1 (0.37) PRMT1MAPTMEN1KMT2AHTT
SCHEMBL22848254 0.87 PRMT1 (0.36) PRMT1MAPTMEN1KMT2AHTT
SCHEMBL22848434 0.86 PRMT1 (0.38) PRMT1MAPTMEN1KMT2AHTT
SCHEMBL22849275 0.85 PRMT1 (0.38) PRMT1MAPTMEN1KMT2AHTT
SCHEMBL25165423 0.85 PRMT1 (0.35) PRMT1MAPTMEN1KMT2AHTT
SCHEMBL22848447 0.84
SCHEMBL22849299 0.83 PRMT1 (0.39) PRMT1MAPTMEN1KMT2AHTT
SCHEMBL25849795 0.82 MAPT (0.45) PRMT1MAPTMEN1KMT2AHTT
SCHEMBL22848221 0.80 CYP1A2 (0.33) PRMT1MAPTMEN1KMT2AHTT
SCHEMBL22848433 0.80 PRMT1 (0.57) PRMT1MAPTMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed