SCHEMBL22848437

SCHEMBL22848437

CNN1/C(=C/C=C2C(=O)c3cc4ccccc4cc3C2=O)C(C)(C)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 16/20 0.48
MEN1 O00255 14/20 0.48
KMT2A Q03164 14/20 0.48
HTT P42858 8/20 0.48
USP2 O75604 4/20 0.48
POLB P06746 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
RAB9A P51151 3/20 0.48
NPC1 O15118 1/20 0.48
LMNA P02545 8/20 0.44
ALDH1A1 P00352 6/20 0.42
KDM4E B2RXH2 5/20 0.42
GAA P10253 7/20 0.39
MAPK1 P28482 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
THRB P10828 4/20 0.37
RECQL P46063 4/20 0.37
NPSR1 Q6W5P4 2/20 0.37
S100A4 P26447 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22849343 0.84 MAPT (0.67) MAPTMEN1KMT2AHTTUSP2
SCHEMBL25850859 0.84 MAPT (0.51) MAPTMEN1KMT2AHTTUSP2
SCHEMBL9637127 0.72 MAPT (0.77) MAPTMEN1KMT2AHTTUSP2
SCHEMBL9637124 0.72 MAPT (0.77) MAPTMEN1KMT2AHTTUSP2
SCHEMBL25850036 0.72 MAPT (0.64) MAPTMEN1KMT2AHTTUSP2
SCHEMBL22849287 0.71 MAPT (0.43) MAPTMEN1KMT2AHTTUSP2
SCHEMBL25851503 0.70 MAPT (0.61) MAPTMEN1KMT2AHTTUSP2
SCHEMBL22848394 0.70 MAPT (0.50) MAPTMEN1KMT2AHTTUSP2
SCHEMBL22848518 0.69 MEN1 (0.40) MAPTMEN1KMT2AHTTUSP2
SCHEMBL22848248 0.69 MEN1 (0.40) MAPTMEN1KMT2AHTTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed