Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26356137 | 0.92 | IRAK4 (0.62) | IRAK4FLT3 | |
| SCHEMBL23651509 | 0.91 | IRAK4 (0.76) | IRAK4FLT3 | |
| SCHEMBL31335165 | 0.91 | IRAK4 (0.76) | IRAK4FLT3 | |
| SCHEMBL22849686 | 0.91 | IRAK4 (0.61) | IRAK4FLT3 | |
| SCHEMBL22848757 | 0.90 | IRAK4 (0.60) | IRAK4FLT3 | |
| SCHEMBL24607003 | 0.88 | IRAK4 (0.58) | IRAK4FLT3 | |
| SCHEMBL24607125 | 0.88 | IRAK4 (0.58) | IRAK4FLT3 | |
| SCHEMBL24590659 | 0.87 | IRAK4 (0.57) | IRAK4FLT3 | |
| SCHEMBL22176682 | 0.87 | IRAK4 (0.57) | IRAK4FLT3 | |
| SCHEMBL22848523 | 0.87 | IRAK4 (0.59) | IRAK4FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264499-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |