Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 9/20 | 0.37 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146602 | 0.89 | ERN1 (0.45) | ERN1PTGDR2PIK3CDBRD4 | |
| SCHEMBL2146833 | 0.88 | PTGDR2 (0.39) | ERN1PTGDR2PIK3CDBRD4NSD3 | |
| SCHEMBL2146838 | 0.88 | PTGDR2 (0.39) | ERN1PTGDR2PIK3CDBRD4NSD3 | |
| SCHEMBL2146131 | 0.85 | ERN1 (0.41) | ERN1BRD4 | |
| SCHEMBL2282817 | 0.83 | ERN1 (0.43) | ERN1PTGDR2PIK3CDBRD4 | |
| SCHEMBL1076940 | 0.83 | PTGDR2 (0.44) | PTGDR2PIK3CDBRD4NSD3 | |
| SCHEMBL2313737 | 0.82 | PTGDR2 (0.41) | PTGDR2PIK3CDBRD4NSD3 | |
| SCHEMBL1076509 | 0.81 | PTGDR2 (0.40) | PTGDR2PIK3CDBRD4NSD3 | |
| SCHEMBL12413817 | 0.80 | ERN1 (0.38) | ERN1PTGDR2PIK3CDBRD4NSD3 | |
| SCHEMBL2146543 | 0.80 | PIK3CD (0.37) | ERN1PTGDR2PIK3CDBRD4NSD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201555-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201555-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | ESR1, ESRRA, GPER1 | ERN1 384/4885PTGDR2 428/4885PIK3CD 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.