Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | FABP3 | P05413 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294669 | 1.00 | CLCN2 (0.53) | CLCN2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30294647 | 0.95 | CLCN2 (0.53) | CLCN2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30294377 | 0.89 | IDO1 (0.48) | CLCN2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL22853121 | 0.89 | IDO1 (0.48) | CLCN2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30294798 | 0.87 | MAPK13 (0.47) | CLCN2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL22852997 | 0.87 | MAPK13 (0.47) | CLCN2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL22853350 | 0.85 | CLCN2 (0.49) | CLCN2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30294815 | 0.85 | CLCN2 (0.49) | CLCN2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL22853346 | 0.85 | IDO1 (0.50) | CLCN2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30294440 | 0.85 | IDO1 (0.50) | CLCN2MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |