Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.38 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.38 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.38 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.38 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.38 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.38 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.38 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954688 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 | |
| SCHEMBL13035585 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 | |
| SCHEMBL13076516 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 | |
| SCHEMBL14647711 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 | |
| SCHEMBL24068232 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 | |
| SCHEMBL20635922 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 | |
| SCHEMBL24498092 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 | |
| SCHEMBL14446466 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 | |
| SCHEMBL19954628 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 | |
| SCHEMBL12764255 | 1.00 | TYR (0.58) | TYRPPARGABCB1PTPN1ATP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119280251-A | Application of cycloastragenol in preparation of medicine for preventing and treating epithelial barrier injury | 复旦大学附属华山医院 | 2025-01-10 | — | — | CN | disclosed |
| CN-114306602-B | Application of targeting TERT in regulating skin and hair pigment | 中国科学院上海营养与健康研究所 | 2024-06-11 | — | — | CN | disclosed |
| WO-2023238056-A1 | COMPOSITIONS FOR SEBUM CONTROL | Dyson Operations PTE. LTD. (SG) | 2023-12-14 | — | — | WO | disclosed |
| CN-113797169-B | Cycloastragaloside-flower-shaped lactose particles and preparation method and application thereof | 复旦大学附属中山医院 | 2023-05-16 | — | — | CN | disclosed |
| CN-114306602-A | Application of targeted TERT in regulating skin and hair pigment | 中国科学院上海营养与健康研究所 | 2022-04-12 | — | — | CN | disclosed |
| WO-2022063307-A1 | APPLICATION OF TARGETED TERT IN REGULATING SKIN AND HAIR PIGMENTS | 中国科学院上海营养与健康研究所 | 2022-03-31 | — | — | WO | disclosed |
| CN-113797169-A | Cycloastragenol-flower-shaped lactose microparticle and preparation method and application thereof | 复旦大学附属中山医院 | 2021-12-17 | — | — | CN | disclosed |
| WO-2020263188-A1 | TRITERPENOIDS THAT DECREASE LIPID PRODUCTION IN SEBOCYTES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-12-30 | — | — | WO | disclosed |
| CN-111378002-A | Novel cycloastragenol crystal form A and preparation method thereof | 山东新时代药业有限公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-108498521-B | Application of cycloastragenol in preparation of medicine for inhibiting abdominal aortic aneurysm | 北京大学 | 2020-05-05 | — | — | CN | disclosed |
| CN-110974837-A | Application of cycloastragenol in preparation of medicine for treating or preventing Alzheimer disease | 潘晓东 | 2020-04-10 | — | — | CN | disclosed |
| CN-108992452-A | Application of the cycloastragenol in prevention and treatment myocardial fibrosis | 北京大学 | 2018-12-14 | — | — | CN | disclosed |