Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | VDR | P11473 | 1/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22855033 | 0.87 | GPBAR1 (0.58) | GPBAR1CYP2C9HIF1AVDREPHA2 | |
| SCHEMBL22855051 | 0.87 | CA1 (0.57) | CA1CA2GPBAR1CYP2C9HIF1A | |
| SCHEMBL22855359 | 0.85 | CA1 (0.56) | CA1CA2GPBAR1CYP2C9HIF1A | |
| SCHEMBL22855079 | 0.82 | CA1 (0.52) | CA1CA2VDRST6GAL1 | |
| SCHEMBL28100269 | 0.80 | GPBAR1 (0.68) | CA1CA2GPBAR1CYP2C9HIF1A | |
| SCHEMBL28100268 | 0.80 | GPBAR1 (0.68) | CA1CA2GPBAR1CYP2C9HIF1A | |
| SCHEMBL10518704 | 0.80 | CA1 (0.79) | CA1CA2GPBAR1CYP2C9HIF1A | |
| SCHEMBL30103319 | 0.80 | CA1 (0.79) | CA1CA2GPBAR1CYP2C9HIF1A | |
| SCHEMBL10518709 | 0.80 | CA1 (0.79) | CA1CA2GPBAR1CYP2C9HIF1A | |
| SCHEMBL26425990 | 0.80 | CA1 (0.79) | CA1CA2GPBAR1CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020260558-A1 | 3-MODIFIED ISO-/ISOALLO-LITHOCHOLIC ACID DERIVATIVES OR THEIR HOMO-ANALOGS FOR PREVENTING AND TREATING CLOSTRIDIOIDES DIFFICILE-ASSOCIATED DISEASES | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-30 | — | — | WO | disclosed |
| US-20160326086-A1 | 4-HYDROXYBUTYRIC ACID ANALOGS | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2016-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326086-A1 | 4-HYDROXYBUTYRIC ACID ANALOGS | HCRTR2, HCRTR1, HTR2B | CA1 1490/4885CA2 351/4885GPBAR1 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.