SCHEMBL22855985

SCHEMBL22855985

CC(C)C(=O)Nc1ccc(COC(=O)NC(C)(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 2/20 0.46
MLYCD O95822 1/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
KDM4E B2RXH2 1/20 0.43
NPSR1 Q6W5P4 2/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
MAPK1 P28482 1/20 0.42
LTA4H P09960 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22855959 0.84 MEN1 (0.55) MEN1KMT2ASMN1; SMN2L3MBTL1LMNA
SCHEMBL18268264 0.84 MEN1 (0.52) MEN1KMT2ASMN1; SMN2L3MBTL1LMNA
SCHEMBL22394067 0.83 MEN1 (0.53) MEN1KMT2ASMN1; SMN2L3MBTL1LMNA
SCHEMBL21671263 0.82 MEN1 (0.56) MEN1KMT2ASMN1; SMN2LMNAMLYCD
SCHEMBL25002073 0.81 MEN1 (0.54) MEN1KMT2ASMN1; SMN2LMNAMLYCD
SCHEMBL19042827 0.81 MEN1 (0.58) MEN1KMT2ASMN1; SMN2LMNAMLYCD
SCHEMBL22551271 0.81 MEN1 (0.49) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL27666773 0.81 KMT2A (0.50) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL19618196 0.80 MEN1 (0.53) MEN1KMT2ASMN1; SMN2LMNAMLYCD
SCHEMBL27805750 0.79 MEN1 (0.43) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200405881-A1 CELL BASED METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENT DELIVERY AND TREATMENTS USING SAME UNIVERSITY OF WASHINGTON (US) 2020-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200405881-A1 CELL BASED METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENT DELIVERY AND TREATMENTS USING SAME CXCL12, CD47, CD44 MEN1 1591/4885KMT2A 3719/4885SMN1; SMN2 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.