SCHEMBL22855997

SCHEMBL22855997

CCCCCC(CC)COC(=O)C1CCCC(C(=O)OCC(CC)CCCCC)C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.48
TSHR P16473 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
ATM Q13315 1/20 0.48
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
ALDH1A1 P00352 4/20 0.43
CA2 P00918 1/20 0.43
RECQL P46063 1/20 0.41
EPHX2 P34913 2/20 0.40
LMNA P02545 2/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
MMP14 P50281 1/20 0.36
ZDHHC7 Q9NXF8 1/20 0.36
ADRB2 P07550 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22856455 0.99 CYP3A4 (0.50) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL1296436 0.96 CYP3A4 (0.53) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL1297549 0.95 CYP3A4 (0.47) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL1296920 0.92 EPHX2 (0.47) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL1325393 0.92 CYP3A4 (0.52) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL1296931 0.91 EPHX2 (0.40) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL1297617 0.91 EPHX2 (0.47) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL1296852 0.91 EPHX2 (0.47) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL1297031 0.91 EPHX2 (0.47) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL1297410 0.91 EPHX2 (0.47) CYP3A4TSHRTDP1ATMPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220185989-A1 CYCLOHEXANE DICARBOXYLATE MIXED ESTER COMPOSITIONS USEFUL AS PLASTICIZERS EASTMAN CHEMICAL COMPANY (US) 2022-06-16 US disclosed
WO-2020263595-A1 CYCLOHEXANE DICARBOXYLATE MIXED ESTER COMPOSITIONS USEFUL AS PLASTICIZERS EASTMAN CHEMICAL COMPANY (US) 2020-12-30 WO disclosed