Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GLP1R | P43220 | 8/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21105905 | 1.00 | KMT2A (0.54) | KMT2AMEN1GLP1RCAPN1CYP2D6 | |
| SCHEMBL22856474 | 0.89 | KMT2A (0.53) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL25122775 | 0.89 | KMT2A (0.53) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL24765414 | 0.88 | MEN1 (0.51) | KMT2AMEN1GLP1RCAPN1SMN1; SMN2 | |
| SCHEMBL21786694 | 0.87 | KMT2A (0.54) | KMT2AMEN1GLP1RCAPN1CYP2D6 | |
| SCHEMBL22790865 | 0.87 | MEN1 (0.54) | KMT2AMEN1GLP1RTSHRUSP2 | |
| SCHEMBL22861922 | 0.87 | MEN1 (0.54) | KMT2AMEN1GLP1RTSHRUSP2 | |
| SCHEMBL25123451 | 0.86 | KMT2A (0.50) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL25028591 | 0.86 | KMT2A (0.53) | KMT2AMEN1GLP1RCYP2D6CYP2C9 | |
| SCHEMBL22837784 | 0.86 | KMT2A (0.53) | KMT2AMEN1GLP1RCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148060-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2020264490-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |