SCHEMBL22856800

SCHEMBL22856800

CCCCCCCCCCCCN(CCCCCCCCCCCC)c1nc(Cl)nc2c1ncn2C1OC(COP(=O)(O)CP(=O)(O)O)C(O)C1O

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NT5E P21589 20/20 0.70
CD79B P40259 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22856823 1.00 NT5E (0.70) NT5ECD79B
SCHEMBL26281966 1.00 NT5E (0.70) NT5ECD79B
SCHEMBL22856799 1.00 NT5E (0.70) NT5ECD79B
SCHEMBL23345647 0.88 NT5E (0.53) NT5ECD79B
SCHEMBL23345645 0.88 NT5E (0.53) NT5ECD79B
SCHEMBL23345790 0.86 NT5E (0.54) NT5ECD79B
SCHEMBL23345791 0.86 NT5E (0.54) NT5ECD79B
SCHEMBL26282954 0.86 NT5E (0.54) NT5ECD79B
SCHEMBL19100512 0.86 NT5E (0.76) NT5E
SCHEMBL25359565 0.84 NT5E (0.69) NT5ECD79B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024346-A1 CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2024-01-25 US disclosed
US-20230295213-A1 CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-09-21 US disclosed
US-11530234-B2 CD73 inhibitors and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2022-12-20 US disclosed
US-20210139526-A1 CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH Co.,Ltd. (CN) 2021-05-13 US disclosed
US-10881681-B2 CD73 inhibitors and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295213-A1 CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF ENTPD5, NT5E, ENTPD1 NT5E 2/4885CD79B 2970/4885
US-10881681-B2 CD73 inhibitors and pharmaceutical uses thereof ENTPD5, ENTPD1, NT5E NT5E 3/4885CD79B 2968/4885
US-20240024346-A1 CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF ENTPD5, NT5E, ENTPD1 NT5E 2/4885CD79B 2970/4885
US-11530234-B2 CD73 inhibitors and pharmaceutical uses thereof ENTPD5, ENTPD1, NT5E NT5E 3/4885CD79B 2968/4885
US-20210139526-A1 CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF ENTPD5, ENTPD1, NT5E NT5E 3/4885CD79B 2968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.