Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16387827 | 0.89 | CYP1A2 (0.71) | CYP1A2NAAASIGMAR1 | |
| SCHEMBL23014720 | 0.88 | CYP1A2 (0.56) | CYP1A2MEN1THRBHTTKMT2A | |
| SCHEMBL10648552 | 0.86 | CYP1A2 (0.59) | CYP1A2NAAASIGMAR1SPHK2SPHK1 | |
| SCHEMBL6437482 | 0.85 | CYP1A2 (0.64) | CYP1A2NAAASIGMAR1 | |
| SCHEMBL9591265 | 0.85 | CYP1A2 (0.50) | CYP1A2MEN1THRBHTTKMT2A | |
| SCHEMBL9591269 | 0.85 | CYP1A2 (0.50) | CYP1A2MEN1THRBHTTKMT2A | |
| SCHEMBL598502 | 0.84 | CYP1A2 (0.76) | CYP1A2MEN1THRBHTTKMT2A | |
| SCHEMBL598906 | 0.84 | CYP1A2 (0.76) | CYP1A2MEN1THRBHTTKMT2A | |
| SCHEMBL599105 | 0.84 | CYP1A2 (0.76) | CYP1A2MEN1THRBHTTKMT2A | |
| SCHEMBL599537 | 0.84 | CYP1A2 (0.76) | CYP1A2MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021000041-A1 | IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY | Precision Nanosystems Inc. (CA) | 2021-01-07 | — | — | WO | disclosed |