Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUAK1 | O60285 | 3/20 | 0.50 |
| ▸ | CCND1 | P24385 | 5/20 | 0.46 |
| ▸ | CDK2 | P24941 | 5/20 | 0.46 |
| ▸ | CDK4 | P11802 | 4/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.46 |
| ▸ | CDK9 | P50750 | 3/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22860491 | 1.00 | NUAK1 (0.50) | NUAK1CCND1CDK2CDK4CCNE1 | |
| SCHEMBL29508806 | 1.00 | NUAK1 (0.50) | NUAK1CCND1CDK2CDK4CCNE1 | |
| SCHEMBL29508796 | 0.91 | NUAK1 (0.59) | NUAK1CCND1CDK2CDK4CCNE1 | |
| SCHEMBL22860694 | 0.91 | NUAK1 (0.56) | NUAK1CCND1CDK2CDK4CCNE1 | |
| SCHEMBL22165942 | 0.91 | NUAK1 (0.59) | NUAK1CCND1CDK2CDK4CCNE1 | |
| SCHEMBL29508775 | 0.91 | NUAK1 (0.56) | NUAK1CCND1CDK2CDK4CCNE1 | |
| SCHEMBL29507736 | 0.90 | NUAK1 (0.58) | NUAK1CCND1CDK2CDK4CCNE1 | |
| SCHEMBL22860415 | 0.90 | NUAK1 (0.58) | NUAK1CCND1CDK2CDK4CCNE1 | |
| SCHEMBL22860410 | 0.85 | NUAK1 (0.46) | NUAK1CCND1CDK2CDK4CCNE1 | |
| SCHEMBL29507882 | 0.85 | NUAK1 (0.46) | NUAK1CCND1CDK2CDK4CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003314-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-01-07 | — | — | WO | disclosed |