SCHEMBL22860768

SCHEMBL22860768

COC(=O)CNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.54
▸ EPHX2 P34913 1/20 0.48
▸ CASP3 P42574 2/20 0.43
▸ OPRD1 P41143 1/20 0.43
▸ FABP5 Q01469 2/20 0.43
▸ CXCR2 P25025 1/20 0.42
▸ FABP7 O15540 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400357 1.00 KMT2A (0.54) KMT2AEPHX2CASP3OPRD1FABP5
SCHEMBL12391727 0.95 KMT2A (0.57) KMT2AEPHX2CASP3OPRD1FABP5
SCHEMBL29470973 0.95 KMT2A (0.57) KMT2AEPHX2CASP3OPRD1FABP5
SCHEMBL26352259 0.89 KMT2A (0.51) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL27072523 0.89 KMT2A (0.51) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL21689327 0.88 KMT2A (0.55) KMT2AEPHX2CASP3OPRD1FABP5
SCHEMBL21614492 0.88 KMT2A (0.55) KMT2AEPHX2CASP3OPRD1FABP5
SCHEMBL1667739 0.87 KMT2A (0.62) KMT2AEPHX2CASP3OPRD1FABP5
SCHEMBL30877982 0.87 KMT2A (0.62) KMT2AEPHX2CASP3OPRD1FABP5
SCHEMBL31309934 0.87 KMT2A (0.62) KMT2AEPHX2CASP3OPRD1FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024235132-A9 COMPOUND HAVING BIOLOGICAL ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2025-06-19 — — WO disclosed
WO-2024235128-A9 ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2025-06-19 — — WO disclosed
WO-2025051241-A1 MACROCYCLIC COMPOUND AND ANTIBODY-DRUG CONJUGATE THEREOF 劲方医药科技(上海)股份有限公司 2025-03-13 — — WO disclosed
WO-2024235132-A1 COMPOUND HAVING BIOLOGICAL ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-11-21 — — WO disclosed
WO-2024235128-A1 ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-11-21 — — WO disclosed
WO-2024140903-A1 COMPOSITION OF CD40-BINDING MOLECULE AND PHARMACEUTICAL USE THEREOF 苏州盛迪亚生物医药有限公司 2024-07-04 — — WO disclosed
CN-118236514-A Antibody-glucocorticoid conjugates and uses thereof 津药生物科技(天津)有限公司 2024-06-25 — — CN disclosed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 — — CN disclosed
CN-111228511-B Anti-HER 3 antibody-drug conjugates 第一三共株式会社 2024-06-18 — — CN disclosed
CN-111228510-B Anti-TROP 2 antibody-drug conjugates 第一三共株式会社 2024-06-18 — — CN disclosed
WO-2022135332-A1 STEROID CONJUGATE 映恩生物制药(苏州)有限公司 2022-06-30 — — WO disclosed
CN-113905767-A Traceless linkers and protein conjugates thereof 里珍纳龙药品有限公司 2022-01-07 — — CN disclosed
US-10973924-B2 Antibody-drug conjugate DAIICHI SANKYO COMPANY, LIMITED (JP) 2021-04-13 — — US disclosed
CN-112533951-A anti-MSR 1 antibodies and methods of use thereof 里珍纳龙药品有限公司 2021-03-19 — — CN disclosed
WO-2021001697-A1 NOVEL BORONIC ACID CONTAINING PEPTIDOMIMETICS AS MALARIAL SERINE PROTEASE INHIBITORS LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) 2021-01-07 — — WO disclosed
CN-112004557-A Steroid compounds and antibody conjugates thereof 里珍纳龙药品有限公司 2020-11-27 — — CN disclosed
CN-111228511-A anti-HER 3 antibody-drug conjugates 第一三共株式会社 2020-06-05 — — CN disclosed
CN-111228510-A anti-TROP 2 antibody-drug conjugates 第一三共株式会社 2020-06-05 — — CN disclosed
CN-106163559-B anti-HER 3 antibody-drug conjugates 第一三共株式会社 2020-02-18 — — CN disclosed
CN-105849126-B anti-TROP 2 antibody-drug conjugates 第一三共株式会社 2020-02-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10973924-B2 Antibody-drug conjugate LANCL2, LANCL1, LCLAT1 KMT2A 588/4885EPHX2 2444/4885CASP3 2168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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