Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2281473 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL2281484 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL2286411 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL2282887 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL2281549 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1ALDH1A1EPHX1 | |
| SCHEMBL2286055 | 0.98 | — | — | |
| SCHEMBL2281685 | 0.90 | — | — | |
| SCHEMBL4421115 | 0.76 | TSHR (0.42) | TSHRALDH1A1LMNAMAPT | |
| SCHEMBL4426916 | 0.76 | TSHR (0.42) | TSHRALDH1A1LMNAMAPT | |
| SCHEMBL4420655 | 0.76 | TSHR (0.42) | TSHRALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994273-B2 | Photoactive materials | ROLIC AG (CH) | 2011-08-09 | — | — | US | claimed |
| US-7750185-B2 | Photoactive materials | ROLIC AG (CH) | 2010-07-06 | — | — | US | claimed |
| US-20050288480-A1 | Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked | ROLIC AG (CH) | 2005-12-29 | — | — | US | claimed |
| EP-1386910-A1 | Photoactive materials | Rolic AG (CH) | 2004-02-04 | — | — | EP | claimed |
| US-11874563-B2 | Photoaligning polymer materials | Rolic Technologies AG (CH) | 2024-01-16 | — | — | US | disclosed |
| CN-110997614-B | Method for preparing photoaligned polymeric materials and compositions | 罗利克技术有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20220145182-A1 | METHOD FOR THE PREPARATION OF PHOTOALIGNING POLYMER MATERIALS AND COMPOSITIONS | Rolic Technologies AG (CH) | 2022-05-12 | — | — | US | disclosed |
| US-11261377-B2 | Photoactive polymer materials | ROLIC AG (CH) | 2022-03-01 | — | — | US | disclosed |
| EP-3924325-A1 | METHOD FOR THE PREPARATION OF PHOTOALIGNING POLYMER MATERIALS AND COMPOSITIONS | Rolic Technologies AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| CN-113412251-A | Method and composition for preparing photoalignment polymer material | 罗利克技术有限公司 | 2021-09-17 | — | — | CN | disclosed |
| EP-3665241-B1 | PHOTOALIGNING POLYMER MATERIALS | ROLIC TECH AG (CH) | 2021-04-28 | — | — | EP | disclosed |
| WO-2020165000-A1 | METHOD FOR THE PREPARATION OF PHOTOALIGNING POLYMER MATERIALS AND COMPOSITIONS | Rolic Technologies AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| EP-0844248-B1 | Crosslinkable, photoactive silane derivatives | ROLIC AG (CH) | 2002-07-10 | — | — | EP | disclosed |
| EP-1219651-A1 | Photoactive copolymer | Rolic AG (CH) | 2002-07-03 | — | — | EP | disclosed |
| US-6335409-B1 | LIQUID CRYSTAL ORIENTATION | ROLIC AG (CH) | 2002-01-01 | — | — | US | disclosed |
| EP-0763552-B1 | Curable, photoactive polymeric materials | ROLIC AG (CH) | 2001-09-19 | — | — | EP | disclosed |
| US-6107427-A | Cross-linkable, photoactive polymer materials | ROLIC AG (CH) | 2000-08-22 | — | — | US | disclosed |
| US-5965761-A | CROSSLINKABLE SILANE DERIVAATIVES HAVING A 3-ARYLACRYLIC ACID OR-ACRYLAMIDE GROUP FOR ORIENTING LAYER AND FOR NONSTRUCTURED AND STRUCTURED OPTICAL ELEMENTS AND MULTILAYER SYSTEMS; PHOTOSTABILITY; CONTRAST; RESOLUTION | ROLIC AG (CH) | 1999-10-12 | — | — | US | disclosed |
| EP-0844248-A2 | Crosslinkable, photoactive silane derivatives | Rolic AG (CH) | 1998-05-27 | — | — | EP | disclosed |
| EP-0763552-A2 | Curable, photoactive polymeric materials | Rolic AG (CH) | 1997-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288480-A1 | Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked | C9, F12, DAO | TSHR 4654/4885FAAH 3107/4885TRPV1 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.