Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 14/20 | 0.37 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24704139 | 1.00 | SOS1 (0.37) | SOS1EGFRCNR1CNR2KRAS | |
| SCHEMBL22862685 | 0.89 | EGFR (0.44) | SOS1EGFRKDR | |
| SCHEMBL22862732 | 0.89 | EGFR (0.44) | SOS1EGFRKDR | |
| SCHEMBL29490317 | 0.89 | EGFR (0.44) | SOS1EGFRKDR | |
| SCHEMBL22862579 | 0.87 | SOS1 (0.37) | SOS1EGFRKDR | |
| SCHEMBL22862659 | 0.78 | KDR (0.35) | EGFRKDR | |
| SCHEMBL22862880 | 0.78 | SOS1 (0.51) | SOS1EGFRKDR | |
| SCHEMBL22862730 | 0.78 | SOS1 (0.51) | SOS1EGFRKDR | |
| SCHEMBL22862723 | 0.77 | CA1 (0.40) | EGFR | |
| SCHEMBL22862630 | 0.77 | CA1 (0.40) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021002986-A2 | BAX INHIBITORS AND USES THEREOF | CASE WESTERN RESERVE UNIVERSITY (US) | 2021-01-07 | — | — | WO | disclosed |