Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.61 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | BRD1 | O95696 | 1/20 | 0.46 |
| ▸ | TAF1 | P21675 | 1/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.46 |
| ▸ | BRD8 | Q9H0E9 | 1/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22863303 | 0.93 | BRD4 (0.61) | BRD4BRD9TRIM24BRD1TAF1 | |
| SCHEMBL22863351 | 0.86 | BRD4 (0.59) | BRD4BRD9TRIM24BRD1TAF1 | |
| SCHEMBL22863352 | 0.86 | BRD4 (0.59) | BRD4BRD9TRIM24BRD1TAF1 | |
| SCHEMBL22863373 | 0.83 | BRD4 (0.69) | BRD4BRD9TRIM24BRD1TAF1 | |
| SCHEMBL22863535 | 0.82 | BRD4 (0.58) | BRD4BRD9TRIM24BRD1TAF1 | |
| SCHEMBL22863344 | 0.82 | BRD4 (0.70) | BRD4BRD9TRIM24BRD1TAF1 | |
| SCHEMBL22863524 | 0.81 | BRD4 (0.70) | BRD4BRD9TRIM24BRD1TAF1 | |
| SCHEMBL22863419 | 0.81 | BRD4 (0.70) | BRD4BRD9TRIM24BRD1TAF1 | |
| SCHEMBL22863349 | 0.80 | BRD4 (0.62) | BRD4BRD9TRIM24BRD1TAF1 | |
| SCHEMBL29777112 | 0.80 | BRD4 (0.62) | BRD4BRD9TRIM24BRD1TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002272-A1 | PYRIDINONE-BASED EPIGENETIC MODIFIERS AND USES THEREOF | UNIV ILLINOIS (US) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002272-A1 | PYRIDINONE-BASED EPIGENETIC MODIFIERS AND USES THEREOF | BRD1, BRD2, BRD3 | BRD4 5/4885BRD9 4/4885TRIM24 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.