Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LPO | P22079 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22863264 | 0.83 | KMT2A (0.50) | KMT2ATSHRLPO | |
| SCHEMBL419709 | 0.71 | KMT2A (0.50) | KMT2ATSHRLPO | |
| SCHEMBL14037751 | 0.70 | PDE1A (0.33) | — | |
| Hydrochloric Acid SCHEMBL16540240 | 0.69 | KMT2A (0.48) | KMT2ATSHRLPO | |
| SCHEMBL8415398 | 0.67 | KMT2A (0.56) | KMT2ATSHRLPO | |
| SCHEMBL21441893 | 0.67 | LRRK2 (0.38) | — | |
| SCHEMBL11050545 | 0.67 | KMT2A (0.56) | KMT2ATSHRLPO | |
| SCHEMBL17544816 | 0.67 | KMT2A (0.43) | KMT2ATSHRLPO | |
| SCHEMBL12440668 | 0.65 | KMT2A (0.48) | KMT2ATSHRLPO | |
| SCHEMBL6251779 | 0.65 | KMT2A (0.48) | KMT2ATSHRLPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332466-B2 | Pyridinone-based epigenetic modifiers and uses thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210002272-A1 | PYRIDINONE-BASED EPIGENETIC MODIFIERS AND USES THEREOF | UNIV ILLINOIS (US) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002272-A1 | PYRIDINONE-BASED EPIGENETIC MODIFIERS AND USES THEREOF | BRD1, BRD2, BRD3 | KMT2A 286/4885TSHR 3351/4885LPO 4630/4885 |
| US-11332466-B2 | Pyridinone-based epigenetic modifiers and uses thereof | BRD1, BRD2, BRD3 | KMT2A 286/4885TSHR 3351/4885LPO 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.