Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | EEF2K | O00418 | 2/20 | 0.35 |
| ▸ | EEF2 | P13639 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5296495 | 0.98 | CA1 (0.36) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL5287394 | 0.87 | EEF2K (0.41) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL5294411 | 0.86 | CA1 (0.36) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL5286202 | 0.85 | KMT2A (0.47) | MAPTCTDSP1CA1CA2EEF2K | |
| SCHEMBL5327460 | 0.85 | CA1 (0.38) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL5295025 | 0.84 | EEF2K (0.49) | MAPTCA1CA2EEF2KEEF2 | |
| SCHEMBL5293024 | 0.84 | EEF2K (0.49) | MAPTCA1CA2EEF2KEEF2 | |
| SCHEMBL5283652 | 0.84 | EEF2K (0.49) | MAPTCA1CA2EEF2KEEF2 | |
| SCHEMBL5815452 | 0.84 | EEF2K (0.49) | MAPTCA1CA2EEF2KEEF2 | |
| SCHEMBL5303724 | 0.84 | EEF2K (0.49) | MAPTCA1CA2EEF2KEEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189317-A1 | Method for Inhibiting the Activity of DPP-IV and Lowering Blood Glucose Level | NATURALENDO TECH CO., LTD. (KR) | 2011-08-04 | — | — | US | disclosed |
| US-20110168253-A1 | ELECTRODE SUBSTRATE AND PHOTOELECTRIC TRANSFORMATION DEVICE | SAMSUNG SDI CO., LTD. (KR) | 2011-07-14 | — | — | US | disclosed |
| US-20080075792-A1 | Method for inhibiting the activity of DPP-IV and lowering blood glucose level | NATURALENDO TECH CO., LTD. (KR) | 2008-03-27 | — | — | US | disclosed |