Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651323 | 0.91 | KMT2A (0.43) | MAPK1KMT2ANPSR1MEN1TP53 | |
| SCHEMBL31373229 | 0.75 | MEN1 (0.45) | MAPK1KMT2ANPSR1MEN1TP53 | |
| SCHEMBL27107138 | 0.75 | MEN1 (0.45) | MAPK1KMT2ANPSR1MEN1TP53 | |
| SCHEMBL23865174 | 0.74 | HPGD (0.52) | MAPK1ATMKMT2ANPSR1MEN1 | |
| SCHEMBL25151377 | 0.73 | MAPK1 (0.61) | ADORA2AMAPK1ATMKMT2AMEN1 | |
| SCHEMBL16092693 | 0.72 | MAPK1 (0.56) | MAPK1ATMKMT2ANPSR1MEN1 | |
| SCHEMBL6314167 | 0.71 | HPGD (0.47) | ADORA2AMAPK1ATMKMT2ANPSR1 | |
| SCHEMBL7603053 | 0.71 | MEN1 (0.56) | MAPK1ATMKMT2ANPSR1MEN1 | |
| SCHEMBL27106513 | 0.70 | ATM (0.43) | ADORA2AMAPK1ATMKMT2ANPSR1 | |
| SCHEMBL20505282 | 0.70 | HPGD (0.49) | KMT2ANPSR1MEN1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021000935-A1 | HPK1 INHIBITORS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2021-01-07 | — | — | WO | disclosed |