Lactic Acid

SCHEMBL2286708

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nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1 DRD2 DRD3 DRD4 HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HRH1 HTR2A PDE3A SIGMAR1

The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	TP53	P04637	1/20	0.69

▸	OR51E2	Q9H255	1/20	0.43

▸	CYP1A2	P05177	1/20	0.42

▸	SMN1; SMN2	Q16637	1/20	0.41

▸	CYP2C9	P11712	1/20	0.40

▸	TSHR	P16473	1/20	0.40

▸	SLC22A6	Q4U2R8	1/20	0.38

▸	TET2	Q6N021	3/20	0.38

▸	KDM4A	O75164	2/20	0.38

▸	KDM4C	Q9H3R0	2/20	0.38

▸	KDM2A	Q9Y2K7	2/20	0.38

▸	TET3	O43151	1/20	0.38

▸	FFAR3	O14843	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Lactic Acid SCHEMBL13505613	1.00	TP53 (0.69)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL7026852	1.00	TP53 (0.69)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL4263083	1.00	TP53 (0.69)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL419437	1.00	TP53 (0.69)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL41708	1.00	TP53 (0.69)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL424598	1.00	TP53 (0.69)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL4261279	1.00	TP53 (0.69)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL3845012	1.00	TP53 (0.69)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL5269783	1.00	TP53 (0.69)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9
Lactic Acid SCHEMBL15008846	0.97	TP53 (0.65)	TP53OR51E2CYP1A2SMN1; SMN2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2045292-B1	ALIPHATIC POLYESTER COMPOSITION AND METHOD FOR PRODUCING THE SAME	KUREHA CORP (JP)	2014-01-22	—	—	EP	disclosed
US-8003721-B2	Aliphatic polyester composition and method for producing the same	KUREHA CORPORATION (JP)	2011-08-23	—	—	US	disclosed
US-20090275692-A1	Alphatic polyester composition and method for producing the same	KUREHA CORPORATION (JP)	2009-11-05	—	—	US	disclosed
EP-2045292-A1	ALIPHATIC POLYESTER COMPOSITION AND METHOD FOR PRODUCING THE SAME	Kureha Corporation (JP)	2009-04-08	—	—	EP	disclosed