Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 20/20 | 0.70 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.70 |
| ▸ | HSD17B4 | P51659 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359682 | 1.00 | HSD17B2 (0.70) | HSD17B2HSD17B1HSD17B4 | |
| SCHEMBL22867938 | 0.88 | HSD17B2 (0.72) | HSD17B2HSD17B1HSD17B4 | |
| SCHEMBL22867272 | 0.86 | HSD17B2 (0.73) | HSD17B2HSD17B1HSD17B4 | |
| SCHEMBL22867220 | 0.86 | HSD17B2 (0.73) | HSD17B2HSD17B1HSD17B4 | |
| SCHEMBL22867347 | 0.85 | HSD17B2 (0.88) | HSD17B2HSD17B1HSD17B4 | |
| SCHEMBL30359818 | 0.84 | HSD17B2 (0.77) | HSD17B2HSD17B1HSD17B4 | |
| SCHEMBL22867547 | 0.84 | HSD17B2 (0.77) | HSD17B2HSD17B1HSD17B4 | |
| SCHEMBL30359606 | 0.84 | HSD17B2 (0.77) | HSD17B2HSD17B1HSD17B4 | |
| SCHEMBL22867266 | 0.84 | HSD17B2 (0.77) | HSD17B2HSD17B1HSD17B4 | |
| SCHEMBL30359590 | 0.82 | HSD17B2 (1.00) | HSD17B2HSD17B1HSD17B4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003295-A1 | MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |