SCHEMBL22869040

SCHEMBL22869040

CC1(C)c2ccccc2-c2cc(-c3nc(-c4cccc(-c5ccccc5)c4)c4ccccc4n3)c3ccccc3c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
NUDT1 P36639 3/20 0.37
ADORA2A P29274 6/20 0.37
RORC P51449 1/20 0.34
WHR1 P49842 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NR1I3 Q14994 3/20 0.33
CYP1A2 P05177 3/20 0.33
CYP3A4 P08684 2/20 0.33
VDR P11473 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2B6 P20813 1/20 0.33
AHR P35869 1/20 0.33
CYP2D6 P10635 2/20 0.32
CYP2C19 P33261 2/20 0.32
CLK4 Q9HAZ1 2/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22868658 0.88 MEN1 (0.41) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL22869047 0.86 MEN1 (0.50) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL22697845 0.84 MEN1 (0.41) MEN1KMT2AATMADORA2ARORC
SCHEMBL22697803 0.84 MEN1 (0.40) MEN1KMT2AATMADORA2AWHR1
SCHEMBL19196080 0.84 MEN1 (0.44) MEN1KMT2AATMADORA2AWHR1
SCHEMBL22697631 0.84 MEN1 (0.40) MEN1KMT2AATMADORA2ARORC
SCHEMBL22880561 0.83 MEN1 (0.43) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL23936140 0.82 MEN1 (0.39) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL19196055 0.81 ATM (0.50) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL18456126 0.81 MEN1 (0.39) MEN1KMT2AATMNUDT1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210005822-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-07 US disclosed