Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10211519 | 0.90 | DPP4 (0.49) | DPP4KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL10211521 | 0.87 | KDM4E (0.39) | DPP4KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL13322106 | 0.83 | KDM4E (0.39) | DPP4KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL27697877 | 0.81 | NR5A1 (0.39) | DPP4KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL11233870 | 0.79 | GSK3B (0.35) | KDM4ETDP1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL10599245 | 0.75 | DPP4 (0.56) | DPP4KDM4ELOXALDH1A1 | |
| SCHEMBL620464 | 0.74 | — | — | |
| SCHEMBL3199262 | 0.74 | KDM4E (0.32) | KDM4ETDP1ALDH1A1L3MBTL1GAA | |
| SCHEMBL223822 | 0.71 | — | — | |
| Ether SCHEMBL27805371 | 0.70 | KDM4E (0.35) | KDM4ETDP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021002473-A1 | NRF2-ACTIVATING COMPOUND | 千寿製薬株式会社 | 2021-01-07 | — | — | WO | disclosed |