Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ARNT | P27540 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18575963 | 0.82 | KMT2A (0.48) | KMT2ANPC1TLR9EPAS1ALDH1A1 | |
| SCHEMBL1022338 | 0.80 | KMT2A (0.46) | KMT2ANPC1TLR9EPAS1ALDH1A1 | |
| SCHEMBL6392936 | 0.79 | KMT2A (0.48) | KMT2ANPC1TLR9EPAS1ALDH1A1 | |
| SCHEMBL18053286 | 0.78 | EPAS1 (0.55) | KMT2ANPC1TLR9EPAS1ALDH1A1 | |
| SCHEMBL22871835 | 0.78 | KMT2A (0.46) | KMT2ANPC1TLR9EPAS1ALDH1A1 | |
| SCHEMBL18053285 | 0.78 | EPAS1 (0.56) | KMT2ANPC1TLR9EPAS1ALDH1A1 | |
| SCHEMBL15882489 | 0.75 | KMT2A (0.46) | KMT2ANPC1TLR9EPAS1ALDH1A1 | |
| SCHEMBL13900945 | 0.72 | POLB (0.54) | KMT2AALDH1A1MEN1POLBGFER | |
| SCHEMBL5285381 | 0.71 | KMT2A (0.58) | KMT2ANPC1TLR9ALDH1A1MEN1 | |
| SCHEMBL5288051 | 0.70 | KMT2A (0.57) | KMT2ANPC1TLR9ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ACADEMIA SINICA (TW) | 2021-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ST6GAL1, NEU1, GALNT1 | KMT2A 1743/4885NPC1 871/4885TLR9 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.