Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 11/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.37 |
| ▸ | STS | P08842 | 6/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22872118 | 0.81 | ESR2 (0.33) | — | |
| SCHEMBL23996080 | 0.79 | APP (0.37) | HSD17B1HSD17B2STS | |
| SCHEMBL22872135 | 0.76 | DAO (0.37) | HSD17B1HSD17B2STSARSNCA | |
| SCHEMBL18133449 | 0.68 | MPL (0.35) | AR | |
| SCHEMBL23552167 | 0.68 | ESR1 (0.41) | HSD17B1HSD17B2 | |
| SCHEMBL22872112 | 0.67 | ESR1 (0.38) | HSD17B1HSD17B2AR | |
| SCHEMBL4451075 | 0.66 | AR (0.46) | AR | |
| SCHEMBL5541865 | 0.65 | — | — | |
| SCHEMBL17365885 | 0.65 | EPHX2 (0.43) | HSD17B1HSD17B2STS | |
| SCHEMBL22872111 | 0.64 | APP (0.37) | HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279565-A2 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2023-11-22 | — | — | EP | disclosed |
| EP-3763802-B1 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2023-09-06 | — | — | EP | disclosed |
| US-11168255-B2 | Thiophene compound, liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-11-09 | — | — | US | disclosed |
| EP-3763802-A1 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2021-01-13 | — | — | EP | disclosed |