Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 6/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | DRD5 | P21918 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22872142 | 0.95 | CYP3A4 (0.42) | QPCTPDE3BPDE3ACYP3A4CYP2C9 | |
| SCHEMBL23346099 | 0.85 | QPCT (0.43) | QPCTPDE3BPDE3ACYP3A4CYP2C9 | |
| SCHEMBL23542784 | 0.85 | QPCT (0.35) | QPCTPDE3BPDE3ACYP3A4CYP2C9 | |
| SCHEMBL22872119 | 0.84 | QPCT (0.41) | QPCTPDE3BPDE3ACTSKCTSC | |
| SCHEMBL22872136 | 0.83 | QPCT (0.42) | QPCTPDE3BPDE3ACYP3A4CYP2C9 | |
| SCHEMBL23552119 | 0.83 | QPCT (0.43) | QPCTPDE3BPDE3ACYP3A4CYP2C9 | |
| SCHEMBL23346100 | 0.82 | QPCT (0.41) | QPCTPDE3BPDE3ACYP3A4CYP2C9 | |
| SCHEMBL23346097 | 0.82 | QPCT (0.41) | QPCTPDE3BPDE3APDK2ESR1 | |
| SCHEMBL27027379 | 0.81 | ESR1 (0.38) | QPCTCYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL22872145 | 0.81 | QPCT (0.37) | QPCTPDE3BPDE3ACTSKCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279565-A2 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2023-11-22 | — | — | EP | disclosed |
| EP-3763802-B1 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2023-09-06 | — | — | EP | disclosed |
| US-11359142-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2022-06-14 | — | — | US | disclosed |
| US-11168255-B2 | Thiophene compound, liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-11-09 | — | — | US | disclosed |
| US-20210189241-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2021-06-24 | — | — | US | disclosed |
| EP-3839009-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-3763802-A1 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2021-01-13 | — | — | EP | disclosed |