Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21064062 | 0.95 | CHRM2 (0.34) | CHRM2CHRM1CHRM3HPGDTSHR | |
| SCHEMBL28201308 | 0.89 | CHRM2 (0.39) | CHRM2CHRM1CHRM3MAPK1TSHR | |
| SCHEMBL4499031 | 0.85 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL3295142 | 0.85 | MAPK1 (0.33) | MAPK1TSHR | |
| SCHEMBL22874559 | 0.83 | TSHR (0.35) | MAPK1HPGDTSHR | |
| SCHEMBL21064053 | 0.83 | TSHR (0.35) | MAPK1HPGDTSHR | |
| SCHEMBL3296871 | 0.83 | TSHR (0.35) | MAPK1HPGDTSHR | |
| SCHEMBL18361332 | 0.83 | TSHR (0.35) | MAPK1HPGDTSHR | |
| SCHEMBL21064071 | 0.83 | TSHR (0.35) | MAPK1HPGDTSHR | |
| SCHEMBL18361370 | 0.83 | TSHR (0.35) | MAPK1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009519-A1 | HISTONE DEACETYLASE INHIBITORS | BIOMARIN PHARMACEUTICAL INC. | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009519-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC2, HDAC3 | CHRM2 4836/4885CHRM1 4856/4885CHRM3 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.